It's so so difficult to say, theres so many types of paint that aren't compatible with fibreglassing resins. When in doubt, it's definitely safer to say it isnt compatible and use PVA release agent.

Thanks - I guess technically I want to use the guitar as a plug to make a mould. It is a solid body and want to understand if the various release wax required etc. will prevent the original lacquer finish from being damaged by the mould material - which I guess would be glass fibre? 

I would like to make a clone of my guitar in CF using my guitar as a mould. Do you think I do this without destroying the finish on my guitar?

Thanks