No, you'll possibly be alright. Always test prior to using it on your parts though. There are way more 2k paints that are incompatible with ester based resins than there are ones that are compatabile.
Personally, I wouldn't use automotive products. I know plenty of people on here do, so I know there are some that work, but I have attempted it 6 times with different 2k automotive paints, and each time resulted in failure. I don't do it any more. You could have more luck with 2k marine products, but they are more expensive and then you might as well go with Duratec anyway. Duratec is made for the job and will work every time. Otherwise, PVA is guaranteed success, it just requires a little bit of post-finishing work.